Dr Helen Hughes

1. Duggan, S., O’Donovan, O., Cummins, W., Hughes, H. and, Owens, E. 'Thiolated polymers as mucoadhesive drug delivery systems', (2017), European Journal of Pharmaceutical Sciences, 100, pp. 64-78.

2. Duggan, S., Hughes, H., Owens, E., Duggan, E., Cummins, W. and O’ Donovan, O. (2016a) 'Synthesis and characterisation of mucoadhesive thiolated polyallylamine', International Journal of Pharmaceutics, 499(1–2), pp. 368-375.

3. Duggan, S., O’Donovan, O., Owens, E., Duggan, E., Hughes, H. and Cummins, W., (2016), ‘Comparison of the mucoadhesive properties of thiolated polyacrylic acid to thiolated polyallylamine’, International Journal of Pharmaceutics, 498 (1-2), pp. 245-253.

4. Duggan, S., O’Donovan, O., Owens, E., Duggan, E., Hughes, H. and Cummins, W. (2016)Duggan, S., O’Donovan, O., Owens, E., Cummins, W. and Hughes, H. (2015) 'Synthesis of mucoadhesive thiolated gelatin using a two-step reaction process', European Journal of Pharmaceutics and Biopharmaceutics, 91(0), pp. 75-81.

5. Tan S. P., O’Sullivan L., Prieto M. L., McLoughlin P., Lawlor P. G., Hughes H. and Gardiner G. E., “Development of a novel antimicrobial seaweed extract-based hydrogel wound dressing”, International Journal of Pharmaceutics, 456, 10-20, (2013)

6. Prieto ML, O’Sullivan L, Tan SP, McLoughlin P, Hughes H, Gutierrez M, Lane JA, Hickey R, Lawlor PG, Gardiner GE,Evaluation of the efficacy and safety of a marine-derived Bacillus strain for use as an in-feed probiotic for newly weaned pigs, PLOS, 9, 2, 1-10, (2014)

7. Prieto M L, O’Sullivan L, Tan S P, McLoughlin P, Hughes H, Gutierrez M, Lane J, Hickey R, Lawlor P, Gardiner G, “In vitro assessment of marine Bacillus for use as livestock probiotics”, Marine Drugs, 12, 5, 2422 – 2445, (2014)

8. Elsiddig R, Hughes H, Owens E, O’ Reilly N J., O’Grady D, McLoughlin P, “Kinetic and thermodynamic evaluation of phosphate ions binding onto sevelamer hydrochloride”, International Journal of Pharmaceutics”, 474, 25-32, (2014)

9. Prieto M. L, O’Sullivan L, Tan S. P, McLoughlin P, Hughes H, O’Connor P. M, Cotter P. D., Lawlor P. G. and Gardiner G. E., “Assessment of the Bacteriocinogenic Potential of Marine Bacteria Reveals Lichenicidin Production by Seaweed-Derived Bacillus spp.”, Mar. Drugs, 10, 2280-2299, (2012)

10. Tan S.P., O’Sullivan L., Prieto M.L. McLoughlin P., Lawlor P.G., Hughes H. and Gardiner G.E. (2012) “Antimicrobials from Marine Macroalgae: Isolation, Characterisation and Applications in Functional Foods”, Bioactive compounds from marine foods: Plant and animal sources (Book Chapter) Published by Wiley-Blackwell.

11. HUDSON, S.P., Owens E., Hughes H. and McLoughlin,P., Enhancement and Restriction of Chain Motion in Polymer Networks, Int. Journal of Pharmaceutics, 430, 1-2, 34-41, (2012).

12. Osmani Q; Hughes H; McLoughlin P, “Probing the recognition of molecularly imprinted polymer beads”, Journal of Materials Science, 47, 5, 2218-2227, 2012

13. Walsh R; Osmani Q; Hughes H; Duggan P and McLoughlin P, “Synthesis of imprinted beads by aqueous suspension polymerisation for chiral recognition of antihistamines”, Journal of  Chromatography B-Anal. Tech in the Biomedical and Life Sciences, 879, 30, 3523-3530, 2011.

14. Tan S. P., O´Sullivan L., Prieto M. L., Gardiner G. E., Lawlor P. G., Leonard F., Duggan P., McLoughlin P., and Hughes H., Extraction and Bioautographic-Guided Separation of Antibacterial Compounds from U. lactuca , accepted for publication in the J. of Phycology, 2011

15. O’Sullivan L., Murphy B., McLoughlin P., Duggan P., Lawlor P. G., Hughes H., Gardiner G. E., “Prebiotics from Marine Macroalgae for Human and Animal Health Applications”, Marine Drugs, 8(7), 2038-2064; 2010

16. Murphy V, Hughes H, and McLoughlin, “Enhancement Strategies for Cu(II), Cr(III) and Cr(VI) remediation by a variety of seaweed species”, Journal of Hazardous Materials, 166, 1, 318-326, 2009.

17. Murphy V, Hughes H, and McLoughlin P, Comparative study of Chromium biosorption by red, green and brown seaweed biomass, Chemosphere, 70, 1128-1134, 2008.

18. Osmani Q., Hughes H., Flavin K., Hedin-Dahlstrom J., Allender C. J., Frisby J., McLoughlin P., The use of FTIR and NMR spectroscopies to study pre-polymerisation interactions in nitrogen heterocycles, Analytical and Bioanalytical Chemistry, 391, 1229-1236, 2008

19. Holland N., Duggan P., Owens E., Cummins W., Frisby J., Hughes H., McLoughlin P., Thermal desorption characterisation of molecularly imprinted polymers. Part II: Use of direct probe GC-MS analysis to study cross-linking effects, Analytical and Bioanalytical Chemistry, 391, 1245-1253, 2008

20. Murphy V, Hughes H, and McLoughlin P, A novel study of hexavalent chromium detoxification by selected seaweed species using SEM-EDX and XPS analysis”, Chemical Engineering, 2008.

21. Flavin K, Hughes H., McLoughlin P., The development of a novel smart infrared sensing methodology for residual solvents, Intern. J. Environ. Anal. Chem., 87, 1, 29-42, 2007.

22. Murphy V, Hughes H. and McLoughlin P, An Investigation into the Mechanism of Cu (II) Binding by Red, Green and Brown Macroalgae, Water Research, 41, 731-740, 2007.

23. Flavin K., Mullowney J., Murphy B., Owens E., Kirwan P., Murphy K., Hughes H., and McLoughlin P., The development of novel organically modified sol-gel media for use with ATR/FTIR sensing, Analyst, 132, 224-229, 2007

24. Flavin K, Hughes H., Dobbyn V, Kirwan P, Murphy K, , and McLoughlin P, A comparison of ., 86, 6, 401-415, 2006.

25. Flavin K., Hughes H., and McLoughlin P., Vibrational Spectroscopy, Paper accepted for publication, 2005.

26. Flavin K, Hughes H., Dobbyn V, Kirwan P, Murphy K, Steiner H, Mizaikoff B, and McLoughlin P, Intern. J. Environ. Anal. Chem., Paper accepted for publication, 2005.

27. M. McMahon, F. Regan & H. Hughes, “The determination of total germanium in real food samples including Chinese herbal remedies using graphite furnace atomic absorption spectroscopy”, 2005, accepted by The Journal of Food.

28. Olwill, P. McLoughlin, H. Hughes, M. O’Riordain, “The use of molecularly imprinted sol-gels in Pharmaceutical Separations”, Biosensors & Bioelectronics, 20, 6, 2004,1045-1050

29. Brady,,D. Leane, H.P. Hughes, R.J. Forster, T.E. Keyes, “Electronic Properties of Ru(II) complexes bound to a Bisphenolate Bridge with low-lying pi* orbitals”, Dalton Trans.,  2004, 2. Winner of Hot Paper of the Month.

30. W.R. Browne, C.M. O’Connor, H.P. Hughes, R. Hage, O. Walter, M. Doering, T.F. Gallagher, & J.G. Vos, “Ru(II) and Os(II) polypyridyl complexes of an asymmetric pyrazinyl & pyridyinal-containing 1,2,4-triazole based ligand. J. Chem. Soc., Dalton Trans., 2002, 4048.

31. S. Fanni, T.E. Keyes, C.M. O’Connor, H.P. Hughes, R. Wang, and J.G. Vos, “Excited-state properties of Ruthenium(II) polypyridyl complexes containing asymmetric triazole ligands”, Coord. Chem. Rev., 2000, 208, 77.

32. C.G. Coates, T.E. Keyes, H.P. Hughes, P.M. Jayaweera, J.J. McGarvey, J.G. Vos, “Resonance Raman and Spectroelectrochemical studies of Ruthenium polypyridyl complexes containing a Triazole bridging ligand. Investigation of the lowest excited state in Mononuclear and Dinuclear complexes, containing pyrazine moieties”, J. Phys. Chem., 1998, 102, (26), 5013.

33. C.G. Coates, T.E. Keyes, J.J. McGarvey, H.P. Hughes, J.G. Vos, P.M. Jayaweera, “Resonance Raman Studies of Ruthenium (II) complexes in DNA and Homogenous Media”, Coord. Chem. Rev., 1998, 171,323,

34. H.P. Hughes, J.G. Vos, “Control of Photosubstitution in Dinuclear Ruthenium Polypyridyl complexes by choice of bridging ligand”, Inorg. Chem., 1995, 34, 4001.